New articles in 2021

Beatrix Péter, Imre Boldizsár, Gábor M. Kovács, Anna Erdei, Zsuzsa Bajtay, Alexandra Vörös, Jeremy J. Ramsden, Ildikó Szabó, Szilvia Bősze, Robert Horvath. Natural Compounds as Target Biomolecules in Cellular Adhesion and Migration: From Biomolecular Stimulation to Label-Free Discovery and Bioactivity-Based Isolation. Biomedicines. 2021 Dec; 9(12): 1781. doi: 10.3390/biomedicines9121781 PMCID: PMC8698624

Bulyáki É, Kun J, Molnár T, Papp A, Micsonai A, Vadászi H, Márialigeti B, Kovács AI, Gellén G, Yamaguchi K, Lin Y, So M, Józsi M, Schlosser G, Lee YH, Liliom K, Goto Y, Kardos J. Pathogenic D76N Variant of β₂-Microglobulin: Synergy of Diverse Effects in Both the Native and Amyloid States. Biology (Basel) 2021;10(11):1197. doi: 10.3390/biology10111197.

Kárpáti É, Kremlitzka M, Sándor N, Hajnal D, Schneider AE, Józsi M. Complement Factor H Family Proteins Modulate Monocyte and Neutrophil Granulocyte Functions. Frontiers in Immunology 2021;12:660852. doi: 10.3389/fimmu.2021.660852.

Garam N, Cserhalmi M, Prohászka Z, Szilágyi Á, Veszeli N, Szabó E, Uzonyi B, Iliás A, Aigner C, Schmidt A, Gaggl M, Sunder-Plassmann G, Bajcsi D, Brunner J, Dumfarth A, Cejka D, Flaschberger S, Flögelova H, Haris Á, Hartmann Á, Heilos A, Mueller T, Rusai K, Arbeiter K, Hofer J, Jakab D, Sinkó M, Szigeti E, Bereczki C, Janko V, Kelen K, Reusz GS, Szabó AJ, Klenk N, Kóbor K, Kojc N, Knechtelsdorfer M, Laganovic M, Lungu AC, Meglic A, Rus R, Kersnik Levart T, Macioniene E, Miglinas M, Pawłowska A, Stompór T, Podracka L, Rudnicki M, Mayer G, Rysava R, Reiterova J, Saraga M, Seeman T, Zieg J, Sládková E, Stajic N, Szabó T, Capitanescu A, Stancu S, Tisljar M, Galesic K, Tislér A, Vainumäe I, Windpessl M, Zaoral T, Zlatanova G, Józsi M, Csuka D. FHR-5 Serum Levels and CFHR5 Genetic Variations in Patients With Immune Complex-Mediated Membranoproliferative Glomerulonephritis and C3-Glomerulopathy. Frontiers in Immunology 2021;12:720183. doi: 10.3389/fimmu.2021.720183.

Szilvia Lukácsi, Zsolt Farkas, Éva Saskői, Zsuzsa Bajtay, Krisztina Takács-Vellai. Conserved and Distinct Elements of Phagocytosis in Human and C. elegans. Int. J. Mol. Sci. 2021, 22(16), 8934; Published online 2021 Aug 19. doi: 10.3390/ijms22168934.

Zsolt Matula, Gábor Mikala, Szilvia Lukácsi, János Matkó, Tamás Kovács, Éva Monostori, Ferenc Uher, István Vályi-Nagy. Stromal Cells Serve Drug Resistance for Multiple Myeloma via Mitochondrial Transfer: A Study on Primary Myeloma and Stromal Cells. Cancers 2021, 13(14), 3461. doi: 10.3390/cancers13143461

Nagy-Baló Z, Kiss R, Demeter J, Bödör C, Bajtay Z, Erdei A. BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1. PLoS One. 2021 Jul 20;16(7):e0254853. doi: 10.1371/journal.pone.0254853. eCollection 2021. PMID: 34283878

Erdei A, Kovács KG, Nagy-Baló Z, Lukácsi S, Mácsik-Valent B, Kurucz I, Bajtay Z. New aspects in the regulation of human B cell functions by complement receptors CR1, CR2, CR3 and CR4. Immunol Lett. 2021 Jun 26;237:42-57. doi: 10.1016/j.imlet.2021.06.006. Online ahead of print. PMID: 34186155 Review.

Uzonyi B, Szabó Z, Trojnár E, Hyvärinen S, Uray K, Nielsen HH, Erdei A, Jokiranta TS, Prohászka Z, Illes Z, Józsi M. Autoantibodies Against the Complement Regulator Factor H in the Serum of Patients With Neuromyelitis Optica Spectrum Disorder. Frontiers in Immunology 2021;12:660382. doi: 10.3389/fimmu.2021.660382.

Kozma GT, Mészáros T, Bakos T, Hennies M, Bencze D, Uzonyi B, Győrffy B, Cedrone E, Dobrovolskaia MA, Józsi M, Szebeni J. Mini-Factor H Modulates Complement-Dependent IL-6 and IL-10 Release in an Immune Cell Culture (PBMC) Model: Potential Benefits Against Cytokine Storm. Frontiers in Immunology 2021;12:642860. doi: 10.3389/fimmu.2021.642860.

Poppelaars F, Goicoechea de Jorge E, Jongerius I, Baeumner AJ, Steiner MS, Józsi M, Toonen EJM, Pauly D; SciFiMed consortium. A Family Affair: Addressing the Challenges of Factor H and the Related Proteins. Frontiers in Immunology 2021;12:660194. doi: 10.3389/fimmu.2021.660194.

Józsi M, Uzonyi B. Detection of Complement Factor B Autoantibodies by ELISA. Methods in Molecular Biology 2021;2227:141-145. doi: 10.1007/978-1-0716-1016-9_14

Kovács RÁ, Vadászi H, Bulyáki É, Török G, Tóth V, Mátyás D, Kun J, Hunyadi-Gulyás É, Fedor FZ, Csincsi Á, Medzihradszky K, Homolya L, Juhász G, Kékesi KA, Józsi M, Györffy BA, Kardos J. Identification of Neuronal Pentraxins as Synaptic Binding Partners of C1q and the Involvement of NP1 in Synaptic Pruning in Adult Mice. Frontiers in Immunology 2021;11:599771. doi: 10.3389/fimmu.2020.599771

Kristóf G Kovács, Bernadett Mácsik-Valent, János Matkó, Zsuzsanna Bajtay, Anna Erdei. Revisiting the coreceptor function of complement receptor type 2 (CR2, CD21); coengagement with the B cell receptor (BCR) inhibits the activation, proliferation and antibody production of human B cells. Frontiers in Immunology. 2021. DOI: 10.3389/fimmu.2021.620427

Prechl, J. Why current quantitative serology is not quantitative and how systems immunology could provide solutions. Biologia Futura 72, 37–44 (2021). https://doi.org/10.1007/s42977-020-00061-1

Matkó, J., Tóth, E.A. Membrane nanotubes are ancient machinery for cell-to-cell communication and transport. Their interference with the immune system. Biologia Futura 72, 25–36 (2021). https://doi.org/10.1007/s42977-020-00062-0

Sármay, G. Biologia Futura: Emerging antigen-specific therapies for autoimmune diseases. Biologia Futura 72, 15–24 (2021). https://doi.org/10.1007/s42977-021-00074-4

Z Bajtay. Biologia Futura: stories about the functions of β2-integrins in human phagocytes. Biologia Futura 72, 7-13. 2021. https://doi.org/10.1007/s42977-020-00063-z

A Falus, Z Bajtay. Scientific memory from the early nineties; a common project with professors late János Gergely and Anna Erdei. Biologia Futura 72, 3-5. 2021. https://doi.org/10.1007/s42977-020-00056-y

2021.01.01.