Bence Szikora PhD student   E-mail: szykora17(at)gmail.com

Short CV.:

Scientific interest:

• The role of the neonatal Fc receptor (FcRn) in the function of the immune system
• The diversity of the humoral immune response
• The analysis of the human B cell repertoire with next generation sequencing.

Awards:

• OTDK special prize, 2015
• Best poster award, FIBOK 2018
• Best „Flash” poster presentation award, FIBOK 2018
• Joseph Cours scholarship 2018

Publications:

Schneider Z, Jani PK, Szikora B, Végh A, Kövesdi D, Iliás A, Cervenak J, Balogh P, Kurucz I, Kacskovics I. Overexpression of Bovine FcRn in Mice Enhances T-Dependent Immune Responses by Amplifying T Helper Cell Frequency and Germinal Center Enlargement in the Spleen. Front Immunol. 2015 Jul 20;6:357.
Szikora B, Hiripi L, Bender B, Kacskovics I, Iliás A. Characterization of the interactions of rabbit neonatal Fc receptor (FcRn) with rabbit and human IgG isotypes. PLoS One. 2017 Sep 28;12(9):e0185662. 2017.

Abstracts at international conferences

Schneider Z, Végh A, Cervenak J, Szikora B, Iliás A, Balogh P, Kurucz I, Kacskovics I. 2014. Expanded antigen-specific T helper cell pool accompanied with augmented germinal center formation and IgG diversity in bovine FcRn transgenic mice upon immunization. Presented at Antibody Biology & Engineering: Understanding Antibody Structure, Function, Diversity, and Pathology to Improve Disease Treatment, Lucca, Italy
Schneider Z, Cervenak J, Jani PK, Szikora B, Iliás A, Balogh P, Kurucz I, Kacskovics I. 2015. Transgenic animals that overexpress the neonatal Fc receptor (FcRn) have improved antibody generation. Presented at Tumor Immunology: Multidisciplinary Science Driving Combination Therapy & Antibodies as Drugs: Immunological Scaffolds as Therapeutics. Keystone Symposia on Molecular and cellular Biology, Fairmont Banff Springs, Banff, Alberta, Canada
Schneider Z, Végh A, Cervenak J, Szikora B, Iliás A, Balogh P, Kurucz I, Kacskovics I. 2015. Overexpression of bovine FcRn in mice enhances T-dependent immune responses and expands antibody diversity by amplifying T helper cell frequency and germinal center enlargement. Presented at Global Engage's Biologics Congress, Berlin, Germany

Abstracts and presentations at conferences in Hungary

• Bence Szikora, Attila Ilias, Istvan Kurucz, Imre Kacskovics. The analysis of the diversity of IgG in bovine FcRn transgenic mice. Szeged, Eötvös Collegium Conference 2014
• Bence Szikora, Attila Ilias, Imre Kacskovics. The analysis of the IgG binding of the neonatal Fc receptor (FcRn) and the diversity of the humoral immune response in bFcRn transgenic mice. Pécs, OTDK, 2015
• Bence Szikora, Attila Ilias, Imre Kacskovics. The analysis of the IgG binding of the neonatal Fc receptor (FcRn) and the diversity of the humoral immune response in bFcRn transgenic mice. Budapest, Bolyai conference 2015
• Bence Szikora, László Hiripi, Imre Kacskovics, Attila Ilias. Characterization of the interactions of rabbit FcRn with rabbit and human IgG isotypes. Velence, MIT conference 2015
• Bence Szikora and Imre Kacskovics. CDR3 spectratyping analysis of the BCR repertoire of transgenic mice that overexpress the bovine FcRn. Budapest, PhD day 2016
• Bence Szikora, Anita Marx, Szilárd Póliska, Bálint Bálint László, Orsolya Pipek, István Csabai, Péter K. Jani, Imre Kacskovics. The analysis of the diversity of the humoral immune response of bovine FcRn transgenic mice. Velence, MIT conference 2017
• Bence Szikora, Anita Marx, Orsolya Pipek, István Csabai, Imre Kacskovics. NGS analysis of the B cell repertoire. Budapest, FIBOK conference 2018
• Bence Szikora and Imre Kacskovics. CDR3 spectratyping analysis of the BCR repertoire of transgenic mice that overexpress the bovine FcRn. Budapest, PhD day 2016
• Bence Szikora, Anita Marx, Orsolya Pipek, István Csabai, Péter K. Jani, Imre Kacskovics. The analysis of the diversity of the humoral immune response of bovine FcRn transgenic mice. Budapest, PhD day 2018